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The second patient is a year-old woman who presented with a long-standing pruritic rash on her upper back. Her past medical history was significant only for hypertension. Biopsies were taken from both the back and the ear for histopathologic analysis.
No evidence of interface dermatitis was detected. Amyloidosis is a depositional disorder with diverse etiologies. It affects multiple organ systems, including the skin.
Systemic amyloidosis involves the deposition of amyloid in multiple tissues. Cutaneous amyloidosis is associated sporadically with a myriad of inflammatory disorders. In these conditions, deposited amyloid is keratinocyte derived. In addition to these three forms, cutaneous amyloidosis can also be an incidental histopathologic finding in various neoplasms. Lichen amyloidosis occurs primarily on the shins, although other mainly acral sites may be involved.
In four cases of smooth papules on the aural conchae were reported by Sanchez [ 4 ]. Another similar report of biphasic amyloidosis by Barnadas [ 7 ] involving the auricular canal not only documented Congo Red positivity but also positive staining with anti-keratin antibodies.
There are several case reports of cutaneous amyloidosis of the auricle occurring in the setting of systemic amyloidosis [ 12 , 13 , 14 ]. Head and neck involvement in systemic amyloid is common. The exact relationship between macular and lichenoid amyloidosis is unknown. The auricular concha is a recognized although unusual site for lichen amyloidosis, and here two additional cases are reported.
Inflammation is sparse. Figure 5: Scanning magnification of an auricular papule shown in Fig. Follicular plugging is prominent. Hematoxylin and eosin stain; Mag: 40X. Hematoxylin and eosin stain; Mag: X. Figure 7: An electron micrograph of an auricular papule from patient 1. Figure 9: The globules in Fig.
Dermatology Online Journal
Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed. Lichen amyloidosis is a rare chronic form of cutaneous amyloidosis see this term , a skin disease characterized by the accumulation of amyloid deposits in the dermis, clinically characterized by the development of pruritic, often pigmented, hyperkeratotic papules on trunk and extremities, especially on the shins, and histologically by the deposition of amyloid or amyloid-like proteins in the papillary dermis. Other search option s Alphabetical list. Suggest an update.
Liquen amiloide en las piernas
Roselinno AMF. Fundamentos de Dermatologia. Rio de Janeiro: Editora Atheneu; Sampaio S, Rivitti E.