Brazilian Consensus on second-generation antipsychotics and metabolic disorders. OBJECTIVE: To discuss current aspects of use of antipsychotics considering their metabolic side effects profile, which includes weight gain, dyslipidemias, diabetes and metabolic syndrome. Such metabolic effects increase the risk of mortality by cardiovascular disease, which is the leading cause of death among schizophrenic patients. METHOD: A consensus meeting was held, with participation of endocrinologists and psychiatrists specialists in schizophrenia and, based on a literature review, an article was elaborated emphasizing practical and helpful recommendations to clinicians.

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Fontaine et al. Em se tratando de estabilizadores de humor, fatores adicionais podem estar envolvidos. A molindona associou-se a discreta perda de peso -0,81 kg. Outros estudos apresentaram achados semelhantes. Czobor et al. Simpson et al. McQuade et al. Silverstone et al. McIntyre et al. O ganho de peso, todavia, parece ser menor com a carbamazepina.

Estudo retrospectivo conduzido por Corman et al. Sowell et al. Da mesma forma, Newcomer et al. Howes et al. Henderson et al. Ardizzone et al. Mackin et al. Lund et al. Sernyak et al. Koro et al. Lindenmayer et al. Littrell et al. Mukherjee et al. Sasaki et al. No estudo de Lindenmayer et al. No estudo de Simpson et al. Heldenberg et al. Calandre et al. No estudo transversal aberto de McIntyre et al.

Casey et. Casey et al. Kato et al. Colp R. History of Psychiatry. Rio de Janeiro: Guanabara Koogan; Thonnard-Newmann E.

Phenothiazines and diabetes in hospitalized women. Am J Psychiatry. Weight gain with antidepressants and lithium. J Clin Psychopharmacol. Fava M. Weight gain and antidepressants. J Clin Psychiatry. Epidemiology, implications and mechanisms underlying drug-induced weight gain in psychiatric patients. J Psychiatr Res. Consensus development conference on antipsychotic drugs and obesity and diabetes. Wirshing D.

Schizophrenia and obesity: impact of antipsychotic medications. Estimating the consequences of anti-psychotic induced weight gain on health and mortality rate. Psychiatry Res. Clozapine, diabetes mellitus, hyperlipidemia, and cardiovascular risks and mortality; results of a year naturalistic study. Excess deaths associated with underweight, overweight and obesity. Determinants of overweight and obesity in patients with bipolar disorder. Hyperglycemia associated with the use of atypical antipsychotics.

Rev Bras Psiquiatr. Schizophrenia, the metabolic syndrome and diabetes. Diabet Med. Newer antipsychotic agents, carbohydrate metabolism and cardiovascular risk. Br J Diabetes Vasc Dis. Antipsychotic-induced weight gain: bipolar disorders and leptin. Insulin resistance and increased leptin concentrations in noncompliant schizophrenia patients but not in antipsychotic-naive first-episode schizophrenia patients.

Valproate, lamotrigine, and insulin-mediated risks in women with epilepsy. Ann Neurol. Antipsychotic-induced weight gain : a comprehensive research synthesis. Clozapine, diabetes mellitus, weight gain, and lipid abnormalities: a five-year naturalistic study.

Antipsychotic-induced weight gain and therapeutic response: a differential association. J Clinical Psychopharmacol. Randomized, controlled, double-blind multicenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder. Efectiveness of antipsychotic drugs in patients with chronic schizophrenia.

N Engl J Med. A comparison of weight change during treatment with olanzapine or aripiprazole: results from a randomized, double-blind study. The effect of aripiprazole on insulin resistance in schizophrenia. New York: APA; Abstract Prevalence of obesity in patients receiving depot antipsychotics. Br J Psychiatry. Valproate, bipolar disorder and polycystic ovarian syndrome. Bipolar Disord.

Weight gain in epileptic patients during treatment with valproic acid: a retrospective study. Can J Neurol Sci. Diabetes mellitus among outpatients receiving clozapine: prevalence and clinical-demographic correlates. Hyperglycemic clamp assessment of insulin secretory responses in normal subjects treated with olanzapine, risperidone, or placebo. J Clin Endocrinol Metab. Insulin resistance measured with euglycemic clamps during antipsychotic treatment in schizophrenia [abstract].

Biol Psychiatry. Newcomer JW. Abnormalities of glucose metabolism associated with atypical antipsychotic drugs. A prospective study of impairment in glucose control caused by clozapine without changes in insulin resistance.

Glucose metabolism in patients with schizophrenia treated with atypical antipsychotic agents. Arch Gen Psychiatry. Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine and structural analogs of clozapine. Brain Res. The effect of clozapine on factors controlling glucose homeostasis.

Dwyer DS, Donohoe D. Induction of hyperglycemia in mice with atypical antipsychotics drugs that inhibit glucose uptake. Pharmacol Biochem Behav.

Vestergaard P, Schou M. Does long-term lithium treatment induce Diabetes mellitus? New onset diabetes and atypical antipsychotics.


Medicamentos antipsicóticos

Si un medicamento le causaba insomnio y ansiedad, le daban otro distinto para contrarrestar esos efectos secundarios. En lugar de ello, la medicaron para convertirla en una persona sumisa. A ello se suma el hecho de que los CNA reciben un salario muy bajo, por lo que muchos de ellos deben trabajar largas horas. Los CMS, que supervisan los hogares de ancianos que reciben subsidios de programas federales, declaran que han estado trabajando para corregir las deficiencias detectadas en estas instituciones, incluido el uso inapropiado de medicamentos. Para Kathi Levine y su madre, estos remiendos llegan muy tarde. Manage your email preferences and tell us which topics interest you so that we can prioritize the information you receive. In the next 24 hours, you will receive an email to confirm your subscription to receive emails related to AARP volunteering.


Abuso de antipsicóticos en hogares de ancianos


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